Colorado Rockies vs Florida Keys

The Colorado Rockies pack big mountain scenery within easy reach of a lively city, which makes them perfect for a long weekend. Start in Denver, the Mile High City, where food halls, breweries and green-chile-smothered everything have turned neighborhoods like RiNo, LoHi and Union Station into a serious food scene. Just 30 minutes west, Red Rocks Amphitheatre sits between towering sandstone slabs and is one of the world's most famous places to see a concert, or simply to climb the stairs at sunrise. From there the mountains take over: Trail Ridge Road in Rocky Mountain National Park climbs past 12,000 feet above treeline, and the old mining towns of Idaho Springs and Georgetown, plus the gateway town of Estes Park, make charming bases. With more time, head to Breckenridge, Vail, Glenwood Springs' hot springs pools, Aspen's Maroon Bells and the red rocks of Garden of the Gods near Colorado Springs. Plan ahead: Rocky Mountain National Park requires timed-entry permits in summer and early fall, the Maroon Bells need a shuttle or parking reservation, and the altitude is real, so drink plenty of water and take the first day easy.

The Florida Keys are America's most famous road trip island chain, a necklace of coral islands linked by the Overseas Highway as it hops 113 miles from Key Largo to Key West over 42 bridges and turquoise water. Starting from Miami, you can be snorkeling North America's only living coral barrier reef at John Pennekamp Coral Reef State Park within a couple of hours. Farther south, Islamorada is the sportfishing capital with tarpon feeding at the docks, Marathon has a sea turtle hospital and the soaring Seven Mile Bridge, and Bahia Honda State Park offers some of the best natural beaches in the Keys. The road ends in Key West, a colorful, easygoing town of conch houses, Hemingway's cats, and the nightly sunset celebration at Mallory Square. This plan covers the full Key Largo to Key West run in four days, then adds a day trip by ferry or seaplane to remote Dry Tortugas National Park and its giant brick fort. Navigate by the green mile markers, slow down in Key deer zones, eat plenty of fresh fish and key lime pie, and book Key West hotels early in winter.